Widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. Its indole scaffold is common in pharmaceuticals, making this compound a valuable intermediate in drug discovery. The boronate ester group facilitates palladium-catalyzed coupling with aryl or heteroaryl halides, allowing efficient construction of complex molecules. The presence of a trifluoromethyl group enhances metabolic stability and lipophilicity, which is beneficial in designing bioactive compounds. Commonly employed in the development of medicinal agents targeting neurological disorders, inflammation, and cancer. Also used in materials science for synthesizing fluorescent probes and optoelectronic materials due to the indole’s photophysical properties.