4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1h-indole
95%
Reagent
Code: #243957
CAS Number
955978-82-2
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Room temperature
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl or heteroaryl halides under mild palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target compounds, which is advantageous in designing bioactive molecules. Commonly employed in the synthesis of indole-based derivatives with potential applications in medicinal chemistry, including kinase inhibitors and CNS-active agents.
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