5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
97%
Reagent
Code: #240775
CAS Number
269410-24-4
blur_circular Chemical Specifications
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Molecular Information
Weight
243.11 g/mol
Formula
C₁₄H₁₈BNO₂
thermostat
Physical Properties
Melting Point
120-125°C
Boiling Point
396°C
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds between aromatic systems. Its indole core makes it valuable in the construction of complex indole derivatives, which are common structural motifs in pharmaceuticals and natural products. The boronate ester group provides high stability and reactivity under mild conditions, allowing efficient coupling with aryl or heteroaryl halides. Frequently employed in drug discovery and development for generating libraries of biologically active compounds, especially in the design of serotonin receptor modulators and kinase inhibitors. Also applied in materials science for synthesizing conjugated organic molecules used in optoelectronic devices.
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