2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-5-carbonitrile

98%

Reagent Code: #238433
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CAS Number 1256359-11-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 268.12 g/mol
Formula C₁₅H₁₇BN₂O₂
badge Registry Numbers
MDL Number MFCD11858359
inventory_2 Storage & Handling
Storage -20°C, sealed, dry

description Product Description

Used primarily in organic synthesis as a building block for pharmaceuticals and agrochemicals, this compound serves as a key intermediate in Suzuki-Miyaura cross-coupling reactions. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in the development of complex indole derivatives. These derivatives are often found in bioactive molecules, including kinase inhibitors and serotonin receptor modulators. The nitrile functionality adds further versatility, allowing transformations into tetrazoles, amines, or carboxylic acids for structure-activity relationship studies. It is particularly useful in medicinal chemistry for constructing drug-like scaffolds with improved metabolic stability and binding affinity.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿4,560.00
inventory 1g
10-20 days ฿13,210.00

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