5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)-1H-indole
98%
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing complex indole derivatives. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in drug candidates, which is beneficial in the development of bioactive molecules. It is particularly useful in the preparation of kinase inhibitors and CNS-active compounds. Additionally, it finds application in materials science for building conjugated systems in organic electronics.
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