Used in organic synthesis as an intermediate for pharmaceuticals and bioactive compounds. Its structure supports the development of indole-based drugs, particularly in the creation of thyroid hormone analogs and antitumor agents. Commonly employed in cross-coupling reactions, such as Suzuki and Heck reactions, to build complex aromatic systems for medicinal chemistry research. Also utilized in the synthesis of natural product derivatives and fluorescent probes due to its halogenated aromatic core.