Used as a key intermediate in the synthesis of biologically active indole derivatives, particularly in pharmaceutical research. Its structure allows for selective functionalization at the 3-position, making it valuable in the development of indole-based drugs. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions to construct complex heterocyclic systems. Also utilized in the preparation of serotonin receptor ligands and other neuroactive compounds due to the indole core’s prevalence in central nervous system agents. Its sulfonyl and iodo groups provide orthogonal reactivity, enabling stepwise modifications in multi-step synthetic routes.