Used as a key intermediate in the synthesis of biologically active indole derivatives, particularly in pharmaceutical research. Its structure allows for selective functionalization at multiple sites, making it valuable in the development of kinase inhibitors and anti-inflammatory agents. The presence of the iodo group enables cross-coupling reactions such as Suzuki or Heck reactions, facilitating the construction of complex molecular architectures. Additionally, the sulfonyl and ester groups act as directing or protecting groups during synthesis, enhancing regio- and stereocontrol. Commonly employed in medicinal chemistry for generating compound libraries aimed at targeting central nervous system disorders and cancer-related pathways.