1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
95%
Reagent
Code: #195785
CAS Number
870717-93-4
blur_circular Chemical Specifications
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Molecular Information
Weight
383.269 g/mol
Formula
C₂₀H₂₂BNO₄S
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Registry Numbers
MDL Number
MFCD08276778
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Physical Properties
Melting Point
120-125 °C
Boiling Point
556.4 °C at 760 mmHg
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Storage & Handling
Density
1.21 g/cm3
Storage
-20°C, inert atmosphere
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex indole derivatives. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in pharmaceutical and agrochemical research for constructing biologically active molecules. The phenylsulfonyl group enhances stability and can act as a directing or protecting group during transformations. Commonly employed in medicinal chemistry for developing kinase inhibitors and other therapeutic agents.
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