1-(tert-butoxycarbonyl)-5-(benzyloxy)-1H-indol-2-yl-2-boronic acid
98%
Reagent
Code: #194003
CAS Number
850568-62-6
science Other reagents with same CAS 850568-62-6
blur_circular Chemical Specifications
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Molecular Information
Weight
367.20 g/mol
Formula
C₂₀H₂₂BNO₅
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Registry Numbers
MDL Number
MFCD06659824
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Storage & Handling
Storage
-20°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of indole-based pharmaceuticals, particularly in Suzuki-Miyaura cross-coupling reactions to form biaryl structures. Its boronic acid functionality enables carbon-carbon bond formation under mild conditions, making it valuable in drug discovery for building complex heterocyclic systems. The Boc and benzyloxy protecting groups enhance stability and regioselectivity during reactions, allowing selective modifications at other positions of the indole ring. Commonly employed in the development of serotonin receptor modulators and kinase inhibitors.
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