Used as a key intermediate in the synthesis of indomethacin analogs and other nonsteroidal anti-inflammatory drugs (NSAIDs). Its structure supports the development of compounds with enhanced selectivity and potency in COX-2 inhibition. Also employed in medicinal chemistry research for developing fluorinated heterocyclic compounds with improved metabolic stability and bioavailability. Commonly utilized in the preparation of sulfonamide-based pharmacophores for anticancer and antimicrobial agents.