4-(1H-Indol-2-yl)aniline
95%
Reagent
Code: #192592
CAS Number
21889-05-4
science Other reagents with same CAS 21889-05-4
blur_circular Chemical Specifications
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Molecular Information
Weight
208.26 g/mol
Formula
C₁₄H₁₂N₂
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Registry Numbers
MDL Number
MFCD01719190
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Physical Properties
Melting Point
201-202 °C(Solv: ethanol (64-17-5))
Boiling Point
441.2±20.0 °C(Predicted)
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Storage & Handling
Density
1.229±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of indole-based pharmaceuticals and bioactive compounds. It plays an important role in the development of serotonin receptor modulators and kinase inhibitors due to its structural similarity to endogenous indoleamines. Commonly employed in medicinal chemistry for constructing libraries of compounds targeting neurological disorders, inflammation, and cancer. Its aniline and indole functionalities allow for diverse functionalization, making it valuable in forming complex heterocyclic systems through coupling reactions and cyclizations. Also utilized in the preparation of fluorescent dyes and optical materials owing to its electron-rich aromatic framework.
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