tert-Butyl 4-hydroxy-1H-indole-1-carboxylate
95%
Reagent
Code: #192567
CAS Number
879093-22-8
science Other reagents with same CAS 879093-22-8
blur_circular Chemical Specifications
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Molecular Information
Weight
233.26 g/mol
Formula
C₁₃H₁₅NO₃
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Registry Numbers
MDL Number
MFCD08272253
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Physical Properties
Boiling Point
374.5±34.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a protected intermediate in the synthesis of indole-based pharmaceuticals. The tert-butoxycarbonyl (Boc) group stabilizes the nitrogen during reactions, while the hydroxyl group allows for further functionalization. Commonly applied in the development of serotonin receptor modulators, kinase inhibitors, and other bioactive molecules in medicinal chemistry. Also employed in the preparation of analogs for structure-activity relationship (SAR) studies due to its ease of deprotection and compatibility with various coupling reactions.
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