(1-(tert-Butyldimethylsilyl)-1H-indol-4-yl)boronic acid

≥98%

Reagent Code: #192502
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CAS Number 351457-64-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 275.23 g/mol
Formula C₁₄H₂₂BNO₂Si
badge Registry Numbers
MDL Number MFCD08436007
thermostat Physical Properties
Melting Point 130-135 °C
Boiling Point 352.1±48.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.01±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Inert Gas

description Product Description

Used primarily as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions. It enables the formation of biaryl compounds by coupling with aryl halides, making it valuable in pharmaceutical and agrochemical research. The indole scaffold is common in bioactive molecules, and the presence of the boronic acid group allows for efficient carbon-carbon bond formation. The tert-butyldimethylsilyl (TBS) protecting group stabilizes the indole nitrogen during reactions, ensuring selectivity and compatibility with multi-step synthetic sequences. Commonly employed in the development of drug candidates targeting neurological disorders, inflammation, and cancer.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿3,260.00
inventory 1g
10-20 days ฿9,310.00

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