4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
98%
Reagent
Code: #192493
CAS Number
1256358-95-8
science Other reagents with same CAS 1256358-95-8
blur_circular Chemical Specifications
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Molecular Information
Weight
277.55 g/mol
Formula
C₁₄H₁₇BClNO₂
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Registry Numbers
MDL Number
MFCD11858364
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Physical Properties
Boiling Point
424.9±25.0 °C(Predicted)
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Storage & Handling
Density
1.20±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Inert Gas
description Product Description
Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl frameworks found in bioactive molecules. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in the development of indole-based drug candidates. Commonly applied in research settings for the synthesis of serotonin receptor modulators, anti-inflammatory agents, and kinase inhibitors. Also utilized in the preparation of functional materials and fluorescent probes due to the indole core’s inherent photophysical properties.
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