(4-Chloro-1-methyl-1H-indol-2-yl)boronic acid
95%
Reagent
Code: #192408
CAS Number
912331-32-9
science Other reagents with same CAS 912331-32-9
blur_circular Chemical Specifications
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Molecular Information
Weight
209.44 g/mol
Formula
C₉H₉BClNO₂
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Registry Numbers
MDL Number
MFCD18427579
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Physical Properties
Boiling Point
433.6±48.0 °C(Predicted)
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Storage & Handling
Density
1.31±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Inert Gas
description Product Description
Used in organic synthesis as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. Its boronic acid group facilitates palladium-catalyzed coupling with aryl halides, making it valuable in constructing complex indole derivatives. These derivatives are often found in bioactive molecules, including drug candidates targeting neurological disorders and inflammation. The presence of the chloro and methyl substituents on the indole ring influences reactivity and selectivity, allowing for selective functionalization in multi-step syntheses. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
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