1H-Indole-1-carboxylic acid, 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester
≥95%
Reagent
Code: #191946
CAS Number
1256359-94-0
science Other reagents with same CAS 1256359-94-0
blur_circular Chemical Specifications
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Molecular Information
Weight
377.6701 g/mol
Formula
C₁₉H₂₅BClNO₄
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Registry Numbers
MDL Number
MFCD16036140
thermostat
Physical Properties
Boiling Point
479.5±48.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
-20°C
description Product Description
Used primarily as an intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to form biaryl compounds. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in the development of active pharmaceutical ingredients (APIs). Commonly applied in the preparation of indole-based drug candidates, including those targeting inflammation, cancer, and neurological disorders. The tert-butyl ester group offers stability during reactions and can be easily deprotected when needed. Preferred in research settings for its reliability in generating complex molecular structures with high yields.
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