4,6,7-trifluoro-1H-indole-2-carboxylic acid
97%
Reagent
Code: #191042
CAS Number
1699249-56-3
science Other reagents with same CAS 1699249-56-3
blur_circular Chemical Specifications
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Molecular Information
Weight
215.13 g/mol
Formula
C₉H₄F₃NO₂
thermostat
Physical Properties
Boiling Point
418.8±40.0 °C(Predicted)
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Storage & Handling
Density
1.693±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of selective kinase inhibitors and central nervous system (CNS) active compounds. Its fluorinated indole structure enhances binding affinity and metabolic stability, making it valuable in medicinal chemistry for optimizing drug candidates. It is also employed in the preparation of bioactive molecules targeting inflammation, neurological disorders, and certain cancers. The compound's unique substitution pattern allows for site-specific modifications, facilitating structure-activity relationship (SAR) studies during drug discovery.
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