4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

98%

Reagent Code: #188859
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CAS Number 1256359-96-2

science Other reagents with same CAS 1256359-96-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 261.10 g/mol
Formula C₁₄H₁₇BFNO₂
badge Registry Numbers
MDL Number MFCD16618972
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl frameworks. Its indole core with a boronate ester group enables selective carbon-carbon bond formation, making it valuable in the development of bioactive molecules and drug candidates targeting neurological disorders, inflammation, and cancer. The fluorine substituent enhances binding affinity and metabolic stability in final active compounds, improving their pharmacokinetic profile. Commonly employed in research laboratories and early-stage drug discovery for generating novel indole derivatives with tailored biological activities.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿4,270.00
inventory 1g
10-20 days ฿11,500.00
inventory 5g
10-20 days ฿40,250.00
inventory 100mg
10-20 days ฿2,630.00

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4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
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Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl frameworks. Its indole core with a boronate ester group enables selective carbon-carbon bond formation, making it valuable in the development of bioactive molecules and drug candidates targeting neurological disorders, inflammation, and cancer. The fluorine substituent enhances binding affinity and metabolic stability in final active compounds, improving their pharmacokinetic profile. Commonly employed in research laboratories and early-stage drug discovery for generating novel indole derivatives with tailored biological activities.
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