7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
97%
Reagent
Code: #188785
CAS Number
1394071-77-2
science Other reagents with same CAS 1394071-77-2
blur_circular Chemical Specifications
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Molecular Information
Weight
261.10 g/mol
Formula
C₁₄H₁₇BFNO₂
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Registry Numbers
MDL Number
MFCD09027752
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Physical Properties
Boiling Point
391.6±27.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed
description Product Description
Used as a key intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl structures. Its indole core with boronate ester functionality enables efficient formation of carbon-carbon bonds, making it valuable in developing drug candidates targeting neurological disorders, inflammation, and cancer. The fluorine substituent enhances binding selectivity and metabolic stability in final active compounds. Commonly employed in research settings for lead optimization in medicinal chemistry programs.
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