7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole

95%

Reagent Code: #187746
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CAS Number 327021-84-1

science Other reagents with same CAS 327021-84-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 175.2 g/mol
Formula C₁₁H₁₀FN
thermostat Physical Properties
Melting Point 102-103°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of serotonin receptor modulators, particularly 5-HT6 and 5-HT7 antagonists. It serves as a structural scaffold in developing compounds targeting cognitive disorders, depression, and neurodegenerative diseases like Alzheimer's. Its fluorinated indole core enhances blood-brain barrier penetration and metabolic stability, making it valuable in CNS drug design. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity of novel therapeutics.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,740.00
inventory 1g
10-20 days ฿6,070.00

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7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole
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Used in pharmaceutical research as a key intermediate in the synthesis of serotonin receptor modulators, particularly 5-HT6 and 5-HT7 antagonists. It serves as a structural scaffold in developing compounds targeting cognitive disorders, depression, and neurodegenerative diseases like Alzheimer's. Its fluorinated indole core enhances blood-brain barrier penetration and metabolic stability, making it valuable in CNS drug design. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity of novel therapeutics.
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