7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole
95%
Reagent
Code: #187746
CAS Number
327021-84-1
science Other reagents with same CAS 327021-84-1
blur_circular Chemical Specifications
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Molecular Information
Weight
175.2 g/mol
Formula
C₁₁H₁₀FN
thermostat
Physical Properties
Melting Point
102-103°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of serotonin receptor modulators, particularly 5-HT6 and 5-HT7 antagonists. It serves as a structural scaffold in developing compounds targeting cognitive disorders, depression, and neurodegenerative diseases like Alzheimer's. Its fluorinated indole core enhances blood-brain barrier penetration and metabolic stability, making it valuable in CNS drug design. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity of novel therapeutics.
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