5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

97%

Reagent Code: #186541
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CAS Number 1072009-08-5

science Other reagents with same CAS 1072009-08-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 261.1 g/mol
Formula C₁₄H₁₇BFNO₂
badge Registry Numbers
MDL Number MFCD16987816
thermostat Physical Properties
Boiling Point 397.4±27.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.16±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used in organic synthesis as a key intermediate for cross-coupling reactions, particularly in the preparation of biologically active indole derivatives. Its boronate ester group enables Suzuki-Miyaura coupling, allowing the formation of C–C bonds with aryl or heteroaryl halides. This makes it valuable in pharmaceutical research for constructing complex molecules, especially in the development of drug candidates targeting neurological disorders, inflammation, and cancer. Commonly employed in medicinal chemistry for late-stage functionalization due to its stability and reactivity profile.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,260.00
inventory 500mg
10-20 days ฿14,960.00

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5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
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Used in organic synthesis as a key intermediate for cross-coupling reactions, particularly in the preparation of biologically active indole derivatives. Its boronate ester group enables Suzuki-Miyaura coupling, allowing the formation of C–C bonds with aryl or heteroaryl halides. This makes it valuable in pharmaceutical research for constructing complex molecules, especially in the development of drug candidates targeting neurological disorders, inflammation, and cancer. Commonly employed in medicinal chemistry for late-stage functionalization due to its stability and reactivity profile.
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