5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
97%
Reagent
Code: #186541
CAS Number
1072009-08-5
science Other reagents with same CAS 1072009-08-5
blur_circular Chemical Specifications
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Molecular Information
Weight
261.1 g/mol
Formula
C₁₄H₁₇BFNO₂
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Registry Numbers
MDL Number
MFCD16987816
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Physical Properties
Boiling Point
397.4±27.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used in organic synthesis as a key intermediate for cross-coupling reactions, particularly in the preparation of biologically active indole derivatives. Its boronate ester group enables Suzuki-Miyaura coupling, allowing the formation of C–C bonds with aryl or heteroaryl halides. This makes it valuable in pharmaceutical research for constructing complex molecules, especially in the development of drug candidates targeting neurological disorders, inflammation, and cancer. Commonly employed in medicinal chemistry for late-stage functionalization due to its stability and reactivity profile.
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