1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
97%
Reagent
Code: #183522
CAS Number
1219741-53-3
blur_circular Chemical Specifications
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Molecular Information
Weight
271.16 g/mol
Formula
C₁₆H₂₂BNO₂
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Registry Numbers
MDL Number
MFCD18383812
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Physical Properties
Boiling Point
380.9°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used primarily in organic synthesis as a boronic ester coupling partner in Suzuki-Miyaura cross-coupling reactions. It enables the formation of carbon-carbon bonds, particularly in the construction of biaryl or aryl-heteroaryl frameworks found in pharmaceuticals and agrochemicals. The indole moiety makes it valuable for synthesizing bioactive molecules, including drug candidates targeting neurological disorders, inflammation, and cancer. Its boronate ester group offers stability and reactivity under palladium catalysis, making it suitable for late-stage functionalization in complex molecule assembly. Commonly employed in medicinal chemistry and materials science for building nitrogen-containing aromatic systems with tailored electronic properties.
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