Ethyl 6-(trifluoromethyl)-1H-indole-2-carboxylate
96%
Reagent
Code: #182719
CAS Number
327-21-9
science Other reagents with same CAS 327-21-9
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Molecular Information
Weight
257.21 g/mol
Formula
C₁₂H₁₀F₃NO₂
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of serotonin receptor modulators and other central nervous system agents. Its indole core with electron-withdrawing trifluoromethyl group enhances binding affinity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship studies due to its ability to mimic natural indole derivatives while offering improved pharmacokinetic properties. Also utilized in the preparation of bioactive molecules for research in neuropharmacology and oncology.
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