4,5-Difluoroindolin-2-one
97%
Reagent
Code: #175804
CAS Number
850429-64-0
blur_circular Chemical Specifications
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Molecular Information
Weight
169.13 g/mol
Formula
C₈H₅F₂NO
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Registry Numbers
MDL Number
MFCD04112481
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Physical Properties
Boiling Point
294.7°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports the design of bioactive molecules with enhanced binding affinity and selectivity. Commonly employed in medicinal chemistry research to optimize drug candidates targeting tyrosine kinases and other signaling proteins involved in tumor growth. Also utilized in the preparation of fluorinated analogs to improve metabolic stability and pharmacokinetic properties of new drug entities.
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