4-Chloroindolin-2-one
98%
Reagent
Code: #160261
CAS Number
20870-77-3
blur_circular Chemical Specifications
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Molecular Information
Weight
167.59 g/mol
Formula
C₈H₆ClNO
thermostat
Physical Properties
Melting Point
206-208°C
Boiling Point
340.3°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to its structural similarity to bioactive indole derivatives. Also employed in the preparation of functionalized oxindoles, which show activity in neurological and anti-inflammatory applications. Its chloro-substituent allows for further functionalization via cross-coupling reactions, making it valuable in drug discovery and organic synthesis.
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