1-Boc-3-Bromo-2-methylindole
≥95%
Reagent
Code: #148241
CAS Number
775305-12-9
science Other reagents with same CAS 775305-12-9
blur_circular Chemical Specifications
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Molecular Information
Weight
310.19 g/mol
Formula
C₁₄H₁₆BrNO₂
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Registry Numbers
MDL Number
MFCD05864780
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Physical Properties
Boiling Point
384.4°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and biologically active compounds, particularly in the development of indole-based drug candidates. Its protected indole structure allows selective functionalization at specific sites, making it valuable in medicinal chemistry for building complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions, where the bromine moiety facilitates carbon-carbon bond formation. The Boc group provides stability and solubility during reaction sequences and can be easily removed under mild acidic conditions when needed. Widely applied in research settings for the preparation of serotonin receptor modulators and other neuroactive agents.
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