1-Boc-3-Bromo-2-methylindole

≥95%

Reagent Code: #148241
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CAS Number 775305-12-9

science Other reagents with same CAS 775305-12-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 310.19 g/mol
Formula C₁₄H₁₆BrNO₂
badge Registry Numbers
MDL Number MFCD05864780
thermostat Physical Properties
Boiling Point 384.4°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, dry seal

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals and biologically active compounds, particularly in the development of indole-based drug candidates. Its protected indole structure allows selective functionalization at specific sites, making it valuable in medicinal chemistry for building complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions, where the bromine moiety facilitates carbon-carbon bond formation. The Boc group provides stability and solubility during reaction sequences and can be easily removed under mild acidic conditions when needed. Widely applied in research settings for the preparation of serotonin receptor modulators and other neuroactive agents.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,270.00
inventory 5g
10-20 days ฿5,420.00
inventory 10g
10-20 days ฿10,270.00
inventory 25g
10-20 days ฿20,110.00
inventory 100g
10-20 days ฿76,470.00

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1-Boc-3-Bromo-2-methylindole
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Used as a key intermediate in the synthesis of pharmaceuticals and biologically active compounds, particularly in the development of indole-based drug candidates. Its protected indole structure allows selective functionalization at specific sites, making it valuable in medicinal chemistry for building complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions, where the bromine moiety facilitates carbon-carbon bond formation. The Boc group provides stability and solubility during reaction sequences and can be easily removed under mild acidic conditions when needed. Widely applied in research settings for the preparation of serotonin receptor modulators and other neuroactive agents.
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