1-Boc-5,6-Dichloro-1H-indole
95%
science Other reagents with same CAS 1209183-93-6
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description Product Description
Used in pharmaceutical synthesis as a protected indole intermediate, particularly in the development of kinase inhibitors and other bioactive molecules. The Boc group provides nitrogen protection during coupling reactions, while the dichloro substitution allows for selective cross-coupling, such as Suzuki or Buchwald-Hartwig reactions, to build complex heterocyclic systems. Commonly employed in medicinal chemistry for optimizing lead compounds in drug discovery programs targeting cancer and inflammatory diseases. Its stability and reactivity profile make it suitable for multi-step syntheses requiring selective functionalization.
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