3-(1-Benzyl-5-fluoro-1H-indol-3-yl)-propionic acid ethyl ester
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Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of indole-based derivatives with potential biological activity. The presence of the benzyl group at the nitrogen and fluorine substituent at the 5-position enhances lipophilicity, improves cell membrane permeability, and increases specificity for receptors, supporting its use in research targeting central nervous system agents such as antidepressants or mood modulators, as well as anti-inflammatory compounds. Commonly employed in medicinal chemistry for constructing complex molecules due to the presence of functional groups amenable to further modification. Also utilized in the preparation of analogs for structure-activity relationship (SAR) studies.
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