tert-Butyl 5-bromo-3-formyl-1H-indole-1-carboxylate
95%
Reagent
Code: #145744
CAS Number
325800-39-3
blur_circular Chemical Specifications
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Molecular Information
Weight
324.17 g/mol
Formula
C₁₄H₁₄BrNO₃
thermostat
Physical Properties
Boiling Point
426.7°C
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Storage & Handling
Storage
2-8°C, inert gas atmosphere
description Product Description
Used primarily as an intermediate in pharmaceutical synthesis, this compound plays a key role in constructing complex indole-based structures. Its aldehyde and bromo functional groups allow for diverse chemical transformations, such as cross-coupling reactions and nucleophilic substitutions, making it valuable in the development of bioactive molecules. It is particularly useful in the preparation of serotonin receptor modulators and other central nervous system agents. The tert-butyl carbamate (Boc) group provides nitrogen protection during synthesis, enabling selective reactions at other sites. This compound is also employed in the synthesis of tryptamine and tryptophan derivatives, which are important in drug discovery and medicinal chemistry.
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