5-((tert-Butyldimethylsilyl)oxy)-3-iodo-1H-indazole
95%
Reagent
Code: #87554
CAS Number
1254473-76-1
science Other reagents with same CAS 1254473-76-1
blur_circular Chemical Specifications
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Molecular Information
Weight
374.29 g/mol
Formula
C₁₃H₁₉IN₂OSi
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Registry Numbers
MDL Number
MFCD26096717
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used in organic synthesis as a versatile intermediate, particularly in the development of pharmaceutical compounds. Its structure, featuring both a silyl-protected hydroxyl group and an iodine atom, allows for selective functionalization, making it valuable in constructing complex molecules. Commonly employed in cross-coupling reactions, such as Suzuki or Sonogashira couplings, to introduce indazole derivatives into target structures. Additionally, it serves as a precursor in the synthesis of biologically active molecules, including potential drug candidates targeting various diseases. The tert-butyldimethylsilyl group provides stability during reactions, while the iodine atom acts as a reactive site for further modifications.
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