This chemical is primarily utilized in organic synthesis as a key intermediate for the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in the development of indazole-based compounds, which are known for their biological activity. The tert-butyldimethylsilyl (TBDMS) group serves as a protective group for hydroxyl functionalities, allowing selective reactions to occur at other sites of the molecule. The iodine atom provides a reactive handle for further functionalization through cross-coupling reactions, such as Suzuki or Sonogashira couplings, which are critical in constructing diverse chemical structures. Its application is significant in the synthesis of potential drug candidates, especially in the fields of oncology and neurology, where indazole derivatives are explored for their therapeutic properties.