7-Bromo-5-fluoro-1H-indazole
95%
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Used primarily as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to its ability to form stable heterocyclic structures that interact with biological targets. Commonly employed in the preparation of potent and selective inhibitors targeting enzymes such as p38 MAPK and JAK, which are involved in inflammatory diseases and oncology. Its halogenated structure allows for further functionalization via cross-coupling reactions, making it valuable in structure-activity relationship (SAR) studies during drug discovery. Also utilized in the creation of research compounds for studying neurological disorders due to its affinity for certain CNS receptors.
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