White fungus (Tremella fuciformis) Extract
White fungus (Tremella fuciformis)—often referred to as “snow fungus” or “silver ear mushroom”
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White fungus (Tremella fuciformis)—often referred to as “snow fungus” or “silver ear mushroom”
White fungus (Tremella fuciformis)—often referred to as “snow fungus” or “silver ear mushroom”
Key Benefit
Tremella fuciformis is notably rich in water-soluble polysaccharides. These polysaccharides appear to modulate immune function by enhancing the activity of certain immune cells, such as macrophages, natural killer (NK) cells, and T-cells.
Representative Studies
Kim MK et al. (2021). “Polysaccharides from Tremella fuciformis (Snow Fungus) Enhance Immune Response via Activation of NF-κB and MAPK Pathways in RAW 264.7 Macrophages.” Journal of Microbiology and Biotechnology, 31(3), 369–377. doi: 10.4014/jmb.2011.10017
Xiao X et al. (2015). “Preparation, characterization, and immune-stimulating activity of Tremella polysaccharide iron complex.” Carbohydrate Polymers, 123, 373–381. doi: 10.1016/j.carbpol.2015.01.014
Key Benefit
Tremella fuciformis polysaccharides may help scavenge free radicals and reduce oxidative stress. This activity has been tied to potential protective effects against cellular damage.
Representative Studies
Lin CF et al. (2018). “Antioxidant activities and protective mechanisms of Tremella fuciformis polysaccharides in vitro and in vivo.” International Journal of Biological Macromolecules, 120, 1480–1489. doi: 10.1016/j.ijbiomac.2018.09.145
Chen J & Seviour R. (2007). “Medicinal importance of fungal β-(1→3), (1→6)-glucans.” Mycological Research, 111(6), 635–652. doi: 10.1016/j.mycres.2007.02.011
Key Benefit
Tremella fuciformis is often used in cosmetics and skincare formulations for its hydrating properties. The large water-holding capacity of Tremella polysaccharides can help maintain skin moisture, and antioxidant activity may support anti-aging benefits.
Representative Studies
Wu D et al. (2016). “Water-Holding Capacity and Moisturizing Effect of Polysaccharides from Tremella fuciformis.” Molecules, 21(8), 1002. doi: 10.3390/molecules21081002
Yang H et al. (2019). “Hydration and anti‐oxidation activities of Tremella fuciformis polysaccharide in human skin cells.” Journal of Cosmetic Dermatology, 18(3), 848–855. doi: 10.1111/jocd.12802
Key Benefit
Some studies indicate that Tremella fuciformis components may help regulate inflammatory pathways, thereby potentially aiding in the management of inflammation-related conditions.
Representative Studies
Chen G et al. (2019). “Anti-inflammatory effects of Tremella fuciformis polysaccharides in LPS-stimulated macrophage cells.” Phytomedicine, 61, 152843. doi: 10.1016/j.phymed.2019.152843
Li S et al. (2021). “Immunomodulatory and anti-inflammatory properties of mushroom polysaccharides.” International Journal of Medicinal Mushrooms, 23(1), 1–14. doi: 10.1615/IntJMedMushrooms.2021036974
Key Benefit
Animal model research suggests Tremella fuciformis extracts and polysaccharides might help regulate blood lipids, potentially improving cholesterol balance. Additional hypotheses propose mild hypoglycemic activity.
Representative Study
Xia X et al. (2019). “Tremella fuciformis Polysaccharides: The Effects on Blood Lipid Metabolism and Mechanisms of Action in Hyperlipidemic Mice.” Carbohydrate Polymers, 213, 98–106. doi: 10.1016/j.carbpol.2019.02.008
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