2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
≥98%(HPLC)
Reagent
Code: #238942
CAS Number
628690-75-5
blur_circular Chemical Specifications
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Molecular Information
Weight
407.39 g/mol
Formula
C₂₃H₁₆F₃N₃O
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Storage & Handling
Density
1.31 g/cm3
Storage
-20°C, Sealed, Dry
description Product Description
Used in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceutical agents for treating autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Its structure enables selective modulation of JAK enzyme activity, contributing to reduced inflammation and immune system regulation. Due to its fluorinated and heterocyclic components, it exhibits enhanced metabolic stability and binding affinity, making it a valuable intermediate in medicinal chemistry for optimizing drug potency and pharmacokinetic properties.
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