3-Bromo-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol
98%
Reagent
Code: #153486
CAS Number
68479-27-6
blur_circular Chemical Specifications
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Molecular Information
Weight
229.03 g/mol
Formula
C₆H₅BrN₄O
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of phosphodiesterase (PDE) inhibitors, particularly PDE5 inhibitors, which are important in the treatment of erectile dysfunction and pulmonary arterial hypertension. Its structure allows for selective modification to enhance binding affinity and pharmacokinetic properties in drug development. Also employed in the preparation of kinase inhibitors for potential anticancer therapies. Commonly utilized in medicinal chemistry research for scaffold optimization in heterocyclic compound design.
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