Rilmenidine is a centrally acting antihypertensive agent that selectively targets imidazoline I₁ receptors in the brainstem, reducing sympathetic outflow and lowering blood pressure. As a chemical reagent, it is supplied as a white solid with a purity of 94.5-100% by HPLC, conforming to structure by IR and ¹H NMR spectrometry. It is commonly used in pharmaceutical research for developing novel antihypertensives, studying autonomic nervous system regulation, and investigating metabolic effects such as improved insulin sensitivity in models of type 2 diabetes and metabolic syndrome. Not intended for direct clinical use; handle as a research chemical.