Imidazole hydrobromide with low water content is primarily used in organic synthesis as a versatile reagent and catalyst. It plays a significant role in the preparation of pharmaceuticals, particularly in the synthesis of antifungal and antibacterial agents. Its low water content ensures higher stability and reactivity, making it suitable for reactions requiring anhydrous conditions. Additionally, it is employed in the production of ionic liquids, which are used in various industrial applications, including electrochemistry and green chemistry processes. Its ability to act as a proton donor or acceptor also makes it valuable in biochemical research, particularly in enzyme studies and protein purification.