1-(3-Bromo-5-(tert-butyl)phenyl)-1H-imidazole
95%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fungicides and antifungal agents. Its structure, featuring bromo at the 3-position, tert-butyl at the 5-position, and imidazole groups on a phenyl ring, supports activity against a range of fungal pathogens, making it valuable in agrochemical research and crop protection formulations. The bromo and imidazole groups allow for further functionalization, such as cross-coupling reactions, enabling the creation of more complex molecules with enhanced biological activity. The tert-butyl group enhances lipophilicity, aiding cell membrane penetration and hydrophobic interactions. It is also employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to interact with biological targets through hydrogen bonding and hydrophobic interactions.
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