AG-120 Racemate

10mM in DMSO

Reagent Code: #134399
fingerprint
CAS Number 1448346-63-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 582.96 g/mol
Formula C₂₈H₂₂ClF₃N₆O₃
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

AG-120 Racemate is primarily used in cancer research, particularly in the study of targeted therapies for certain types of leukemia and solid tumors. It functions as an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1), an enzyme that is abnormally active in some cancers and contributes to the accumulation of oncometabolites that disrupt normal cellular differentiation. By blocking the activity of mutant IDH1, AG-120 Racemate helps restore normal cell differentiation pathways, reducing tumor growth and promoting cancer cell maturation. It is commonly used in preclinical studies to evaluate the efficacy and mechanism of IDH1 inhibition, supporting the development of more effective treatments for IDH1-mutant cancers. Its role as a racemate also allows researchers to compare the biological activity of individual enantiomers during drug optimization.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿4,210.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB