O-(2-Chlorobenzyl)hydroxylamine hydrochloride is primarily used in organic synthesis as a versatile building block for the preparation of various chemical compounds. It serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of drugs targeting neurological disorders and inflammation. The compound is also employed in the creation of chelating agents, which are useful in metal ion sequestration and catalysis. Additionally, it finds application in the production of agrochemicals, contributing to the development of pesticides and herbicides. Its reactivity with carbonyl compounds makes it valuable in the formation of oximes, which are important in analytical chemistry and material science.