Poly(propylene glycol) is widely used in various industries due to its versatile properties. In the pharmaceutical sector, it serves as a solvent, excipient, or base in ointments, creams, and topical formulations. It is also utilized in the production of controlled-release drug delivery systems. In the cosmetics industry, it acts as a humectant, emulsifier, and viscosity modifier in skincare and haircare products.

In industrial applications, it is employed as a lubricant, antifoaming agent, and hydraulic fluid. Additionally, it is a key component in the manufacture of polyurethane foams, adhesives, and sealants. Its water-soluble nature and low toxicity make it suitable for use in food processing as a stabilizer, thickener, or emulsifier. Poly(propylene glycol) also finds applications in the production of inks, coatings, and elastomers, contributing to their flexibility and durability.