6-Hydroxypicolinohydrazide is primarily utilized in the field of organic synthesis and pharmaceutical research. It serves as a key intermediate in the production of various heterocyclic compounds, which are essential in developing new drugs and therapeutic agents. Its structure allows it to act as a versatile building block, particularly in the synthesis of hydrazide derivatives that exhibit potential biological activities. Additionally, it is explored for its chelating properties, making it useful in the development of metal-organic frameworks (MOFs) and coordination chemistry applications. Researchers also investigate its role in designing molecules with antioxidant, antimicrobial, and anti-inflammatory properties, contributing to advancements in medicinal chemistry.