4-Nitrobenzhydrazide is primarily utilized in organic synthesis as a key intermediate for the preparation of various hydrazone derivatives. These derivatives are often explored for their potential biological activities, including antimicrobial, anticancer, and anti-inflammatory properties. Additionally, it serves as a reagent in the development of Schiff bases, which are widely studied for their applications in coordination chemistry and as ligands for metal complexes. The compound is also employed in the synthesis of heterocyclic compounds, which are important in pharmaceutical research and drug discovery. Its nitro group makes it a valuable precursor in reactions involving reduction or further functionalization, contributing to the development of diverse chemical entities.