4-tert-Butylbenzhydrazide is primarily used in organic synthesis as a key intermediate for the preparation of various hydrazone derivatives. These derivatives are often employed in the development of pharmaceuticals, particularly in the synthesis of compounds with potential anti-inflammatory, antimicrobial, and antitumor properties. Additionally, it serves as a building block in the creation of agrochemicals, where it contributes to the formulation of pesticides and herbicides. The compound is also utilized in research laboratories for studying reaction mechanisms and developing novel chemical entities with specific biological activities. Its role in the synthesis of Schiff bases further extends its application in material science, particularly in the design of coordination polymers and metal-organic frameworks.