Ammonium acetate solution is widely used in biochemical research as a buffer in HPLC and LC-MS analyses, ensuring stable pH conditions for accurate separation and detection of compounds. It serves as a source of ammonia in organic synthesis, facilitating reactions like the preparation of acetamides. In molecular biology, it is employed in DNA and RNA precipitation due to its ability to neutralize charges on nucleic acids, aiding in their isolation. Additionally, it acts as a mobile phase modifier in chromatography, improving the separation of polar compounds. Its use in protein crystallography helps maintain protein stability during crystallization processes.