AGN 194078 is primarily utilized in research settings to study its effects on retinoid receptors, particularly in the context of cellular differentiation and apoptosis. It has been explored for its potential role in cancer research, where it may help in understanding the mechanisms of retinoid signaling pathways and their impact on tumor growth. Additionally, AGN 194078 is used in pharmacological studies to investigate its therapeutic potential in diseases influenced by retinoid receptor activity, such as certain skin disorders and cancers. Its application is largely confined to laboratory experiments aimed at elucidating its biological activity and potential clinical relevance.