Used in research to study the renin-angiotensin system, particularly in understanding blood pressure regulation and fluid balance. Acts as a biologically active peptide that binds to angiotensin receptors, including AT1 and AT2 subtypes, making it valuable in cardiovascular and renal physiology studies. Commonly employed in in vitro and in vivo experiments to mimic angiotensin II effects, especially in brain and kidney tissues where it modulates aldosterone release and sympathetic nervous system activity. Also utilized in receptor binding assays to evaluate antagonist potency and receptor subtype selectivity.