Bradykinin is involved in the regulation of blood pressure and plays a key role in the inflammatory response. It causes blood vessels to dilate, leading to lowered blood pressure and increased vascular permeability, which allows immune cells to reach tissues more easily during injury or infection. It is also responsible for pain sensation, as it stimulates nerve endings and contributes to the feeling of pain in inflamed areas. In medicine, bradykinin pathways are targeted in the treatment of hereditary angioedema, where uncontrolled bradykinin activity causes severe swelling. Drugs that inhibit bradykinin receptors or its formation, such as icatibant, are used to manage acute attacks. Additionally, bradykinin contributes to the side effects of certain blood pressure medications like ACE inhibitors, which can cause dry cough due to bradykinin accumulation.