MS-049 is primarily utilized in biochemical research as a selective inhibitor of the enzyme PRMT5 (Protein Arginine Methyltransferase 5). It is employed to study the role of PRMT5 in various cellular processes, including gene expression, RNA splicing, and cell cycle regulation. Researchers use MS-049 to investigate its potential therapeutic effects in diseases where PRMT5 is implicated, such as certain cancers. By inhibiting PRMT5, MS-049 helps in understanding the enzyme's function and its impact on tumor growth and survival, providing insights for developing targeted cancer therapies. Additionally, it is used in preclinical studies to explore its efficacy and safety profile in different biological contexts.